Neural circuit dynamics of working memory
The Princeton Neuroscience Institute seeks talented postdoctoral or more senior researchers for an NIH BRAIN Initiative project to start during the 2019/20 academic year. In collaboration with the University of California, Davis, this multi-investigator project involves studying the neural circuit dynamics underlying working memory during "accumulation-of-evidence" tasks in rodents. See our website here: www.braincogs.org. Our goal is to understand working memory at a brain-wide, integrative level. Brain regions to be investigated include frontal, parietal, and sensory cortices, striatum, hippocampus, and cerebellum, with a view to achieving a whole picture of how these different brain structures work together dynamically to process, store, and transfer information to one another.
The project is a collaborative effort between the research groups of David Tank (firstname.lastname@example.org), Carlos Brody (email@example.com), Mark Goldman (firstname.lastname@example.org), Jonathan Pillow (email@example.com), Sebastian Seung (firstname.lastname@example.org), Sam Wang (email@example.com), and Ilana Witten (firstname.lastname@example.org). Applicants are welcome to contact one or more of the investigators for more information. Successful applicants will take a collaborative approach spanning multiple laboratories. They can take advantage of the thriving and growing neuroscience community at Princeton University as well as working (remotely) with the neuroscience community at UC Davis.
We are currently seeking candidates with experience in rodent behavior, electrophysiological recordings, computational analysis, brain circuit anatomy, and optogenetic manipulations. Activities will be supported by state-of-the-art facilities in the new building of the Princeton Neuroscience Institute, including advanced two-photon imaging and electron microscopy systems located in the Bezos Center for Neural Circuit Dynamics, and by the vibrant and rapidly expanding faculty in Computational Neuroscience and related fields at UC Davis supported by the Initiative in Computational Sciences (http://comphip2017.ucdavis.edu/). Interested applicants must apply online at https://www.princeton.edu/acad-positions/position/12821 and include a cover letter, curriculum vitae, a brief statement of research interests, and contact information for at least two references. The initial term of employment is for one year with the possibility of reappointment based on satisfactory performance and continued funding. A Ph.D. in Neuroscience, Psychology, Physics, Math, Molecular Biology, Computer Science or related field or equivalent is required.
This position is subject to the University's background check policy. Princeton University is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability status, protected veteran status, or any other characteristic protected by law.
Senior research specialist I
The Princeton Neuroscience Institute has a Senior Research Specialist position available for the Circuits of coGnitive Systems collaboration (braincogs.org). This project seeks to understand how multiple brain regions work together to carry out cognitive processing using mice as a model system for mammalian brain function. Our project, funded by the NIH BRAIN initiative, is a collaboration between the research groups of Carlos Brody, Mark Goldman (UC Davis), Jonathan Pillow, Sebastian Seung, David Tank, Sam Wang, and Ilana Witten.
The primary responsibility of this position is to provide technical support for the custom optical and behavioral instrumentation used within the multiple laboratories in our project. These systems will be used for large scale optical recording and optogenetic perturbation studies on the mechanisms of working memory and decision-making. After proper training, the successful candidate will also be expected to assist other researchers with the usage of several commercial instruments (confocal microscope, light sheet microscopes, slide scanner). Work will be performed in conjunction with the recently established Bezos Center for Neural Circuit Dynamics. The successful candidate will work with Bezos Center management and faculty to develop and support the imaging tools and peripheral instrumentation.
Interested applicants must apply online at https://research-princeton.icims.com /jobs/10707/senior-research-specialist-1/job and include a cover letter, curriculum vitae, a brief statement of research interests, and contact information for at least two references.This is initially a one-year position with the possibility of renewal, based on satisfactory funding and performance. A commitment of at least two years is preferred. A bachelor's degree in a science or engineering field is required. A master's or PhD degree is preferred.
The specific duties include the implementation, and maintenance of:
Custom two-photon, and three-photon, microscopes for cellular resolution calcium imaging of neural populations.
Virtual reality systems for rodents.
Custom Wide field fluorescence microscopes for macroscopic imaging of neural dynamics across brain regions.
State of the art systems for combined imaging and optogenetic perturbation at cellular resolution.
Other duties will require to:
Perform recurrent quality control checks on all microscopes. Keep accurate, legible records to monitor instrument performance. In concert with the Imaging Director, complete scheduled and unscheduled system maintenance as needed.
Perform routine laboratory duties including ordering of lab supplies, general lab upkeep, routine maintenance of laboratory equipment. Must be able to lift at least 50 pounds.
A bachelor's degree in a science or engineering field is required. A master's or PhD degree is preferred.
Previous experience in optics and/or imaging is required.
Experience in optical design, mechanical design, instrumentation, and electronics are a plus.
This position is subject to the University's background check policy. Princeton University is an Equal Opportunity/Affirmative Action Employer and all qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity or expression, national origin, disability status, protected veteran status, or any other characteristic protected by law. EEO IS THE LAW